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Coevolution mechanisms that adapt viruses to genetic code variations implemented in their hosts

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Title Coevolution mechanisms that adapt viruses to genetic code variations implemented in their hosts
 
Creator Kumar, Sushil
Kumari, Renu
Sharma, Vishakha
 
Subject codon usage
eukaryotes
nonstandard genetic code
phages
prokaryotes
transfer RNA
translation factors
viruses
 
Description Accepted date: 4 August 2015
Viruses, the preponderant species, are the agents of horizontal
gene transfer between cellular organisms, a major means
for generation of genetic variability that drives evolution in
varying environments. Recent work on virus × host interaction
has led to revision of the conventional idea that the
genetic code of the virus and host must be same so that the
host translational system facilitates efficient, accurate and
complete expression of the infecting viral genome. There is
evidence now that differences between the genetic codes of
viruses and their hosts are not an absolute barrier to virus
multiplication. The recent work on mechanisms by which
viruses overcome the mismatch in codon usage of host versus
theirs is discussed here contextually. Examples of coevolution
of viruses and their hosts, in terms of genetic code
usage, discussed here agree with the concept that their evolution
is reciprocally driven and therefore suggestive of a kind
of long-term interdependent symbiotic relationship between
them.
Grateful thanks are due to Indian National Science Academy for the
grant of an honorary-scientistship to SK and to Director of National
Institute of Plant Genome Research for facilities.
 
Date 2016-03-21T05:47:09Z
2016-03-21T05:47:09Z
2016
 
Type Article
 
Identifier J. Genet., 95: 3-12
0973-7731
http://172.16.0.77:8080/jspui/handle/123456789/629
http://www.ias.ac.in/describe/article/jgen/095/01/0003-0012
10.1007/s12041-016-0612-7
 
Language en_US
 
Publisher Indian Academy of Sciences