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Synthesis of functionalized Cu:ZnS nanosystems and its antibacterial potential

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Title Synthesis of functionalized Cu:ZnS nanosystems and its antibacterial potential
 
Creator Chaliha, C.
Nath, B. K.
Verma, Praveen K.
Kalita, E.
 
Subject Cu:ZnS
MSA
Sodium citrate
Solvothermal
Antibacterial property
 
Description Accepted date: 7 May 2016
Copper doped Zinc Sulfide (Cu:ZnS) nanoparticles were synthesized as potential antibacterial agents, through a solvothermal approach using Mercaptosuccinic acid (MSA) and Sodium citrate (SC) as differential capping agents. Multiple variants of the Cu:ZnS nanoparticles were generated based on the refluxing intervals of the reactions and a choice of the capping agents. The microstructural properties and the elemental composition of the synthesized nanosystems were examined using Scanning Electron Microscopy (SEM) and powder X-ray Diffraction (XRD), along with Energy-Dispersive X-ray spectroscopy (EDX) and Microwave Plasma-Atomic Emission Spectroscopy (MP-AES). The as-synthesized nanosystems were also characterized for their surface attributes using Fourier Transform Infrared spectroscopy (FT-IR), while the optical properties were studied using UV–Vis spectroscopy. The electrostatic stability of the aqueous dispersions of Cu:ZnS was studied as a function of their solvent pH, using Photon Correlation Spectroscopy. For the assessment of the antibacterial properties of the different variants of Cu:ZnS nanosystems, the disk diffusion assay was performed against both Gram-positive and Gram-negative bacteria. The results show a promising antibacterial activity for the Cu:ZnS variants synthesized, with a prominent activity in the MSA@Cu:ZnS nanoparticle making them a novel class of potential antibacterial agents.
The authors wish to acknowledge DBT, Govt. of India, for the Research Grants (Grant No. BT/427/NE/TBP/2013 and BT/258/NE/TBP/2011), UGC, India for the Research Grants (TU/Fin/MBBT/116/05/11-12/64 and F.3-1/2015/DRS-II(SAP-II)) and DBT Strengthening Grant (BT/HRD/01/02/2007). They also thank Dr. Ratan Boruah, Tezpur University for the SEM and EDX analysis. They also sincerely thank Dr. S.K. Ray, Assoc. Prof., Dept. of Molecular Biology and Biotechnology for his inputs.
 
Date 2016-06-21T11:19:09Z
2016-06-21T11:19:09Z
2017
 
Type Article
 
Identifier Arab. J. Chem., (In Press)
1878-5352
http://172.16.0.77:8080/jspui/handle/123456789/659
http://www.sciencedirect.com/science/article/pii/S1878535216300569
10.1016/j.arabjc.2016.05.002
 
Language en_US
 
Publisher Elsevier B.V.