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Biotechnological interventions for production of therapeutic secondary metabolites using hairy root cultures of medicinal plants

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Title Biotechnological interventions for production of therapeutic secondary metabolites using hairy root cultures of medicinal plants
 
Creator Srivastava, V.
Mehrotra, S.
Verma, Praveen K.
 
Subject Agrobacterium
Elicitor
Hairy roots
Medicinal plants
Metabolic pathway
Pharmaceutical molecule
Precursor
Secondary metabolite
 
Description Accepted date: 16 September 2016
The repository of molecules (secondary metabolites) in plants have been identified as an effective candidate to cure human diseases. This immense potential is continuously being utilized by exploiting natural plant resources. Such practices led to environmental imbalances and many natural sites were deserted. This chapter provides current perspectives on plant hairy root cultures as an important model for sustainable therapeutic secondary metabolite production. Here, the imperative interventions of biotechnology to enhance the accumulation of such molecules are discussed. Current research trends for metabolite enhancement through media optimization, elicitation, precursor feeding, metabolic engineering, and upscaling are taken into consideration.
V.S. acknowledges the Council of Scientific and Industrial Research (CSIR), New Delhi, India for financial support (CSIR-Research Associateship). The authors also acknowledge NIPGR for providing the work facility.
 
Date 2016-11-30T08:31:03Z
2016-11-30T08:31:03Z
2016
 
Type Book chapter
 
Identifier In: Dubey SK, Pandey A, Sangwan RS (eds.), Current Developments in Biotechnology and Bioengineering: Crop Modification, Nutrition and Food Production, Vol VI. Elsevier, pp 259-282
978-0-444-63661-4
http://59.163.192.83:8080/jspui/handle/123456789/697
http://www.sciencedirect.com/science/article/pii/B9780444636614000128
http://dx.doi.org/10.1016/B978-0-444-63661-4.00012-8
 
Language en_US
 
Publisher Elsevier B.V.