Alterations in rice chloroplast integrity, photosynthesis and metabolome associated with pathogenesis of Rhizoctonia solani
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Title |
Alterations in rice chloroplast integrity, photosynthesis and metabolome associated with pathogenesis of Rhizoctonia solani
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Creator |
Ghosh, S
Kanwar, P Jha, Gopaljee |
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Subject |
Rhizoctonia solani
photosynthesis rice chloroplast integrity Microbe Biotic |
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Description |
Accepted date: 21/12/2016
Sheath blight disease is caused by a necrotrophic fungal pathogen Rhizoctonia solani and it continues to be a challenge for sustainable rice cultivation. In this study, we adopted a multi-pronged approach to understand the intricacies of rice undergoing susceptible interactions with R. solani. Extensive anatomical alteration, chloroplast localized ROS, deformed chloroplast ultrastructure along with decreased photosynthetic efficiency were observed in infected tissue. GC-MS based metabolite profiling revealed accumulation of glycolysis and TCA cycle intermediates, suggesting enhanced respiration. Several aromatic and aliphatic amino acids along with phenylpropanoid intermediates were also accumulated, suggesting induction of secondary metabolism during pathogenesis. Furthermore, alterations in carbon metabolism along with perturbation of hormonal signalling were highlighted in this study. The gene expression analysis including RNAseq profiling reinforced observed metabolic alterations in the infected tissues. In conclusion, the present study unravels key events associated during susceptible rice-R. solani interactions and identifies metabolites and transcripts that are accumulated in infected tissues. S.G. is supported by SPM fellowship from Council of Scientific and Industrial Research (Govt. of India) and P.K. is supported by Post-Doctoral Research fellowship from Department of Biotechnology (DBT, Govt of India). We acknowledge Nucleome Pvt. Ltd for assistance in RNA Seq. The assistance of NIPGR central instrumentation facilities for sequencing, real time PCR, IRGA and microscopic (stereo-zoom and confocal) analysis are acknowledged. The authors are grateful to the AIRF, JNU, New Delhi for the GCMS facility and AIIMS, New Delhi for TEM facility. This work was supported by core research grant from the National Institute of Plant Genome Research, India and research funding from DBT, Government of India. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. |
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Date |
2017-02-06T04:36:28Z
2017-02-06T04:36:28Z 2017 |
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Type |
Article
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Identifier |
Scientific Reports, 7:41610
2045-2322 http://59.163.192.83:8080/jspui/handle/123456789/722 http://www.nature.com/articles/srep41610 |
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Language |
en_US
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Publisher |
Nature Publishing Group
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