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ProPred1: prediction of promiscuous MHC Class-I binding sites.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title ProPred1: prediction of promiscuous MHC Class-I binding sites.
 
Creator Singh, Harpreet
Raghava, G.P.S.
 
Subject QR Microbiology
 
Description SUMMARY: ProPred1 is an on-line web tool for the prediction of peptide binding to MHC class-I alleles. This is a matrix-based method that allows the prediction of MHC binding sites in an antigenic sequence for 47 MHC class-I alleles. The server represents MHC binding regions within an antigenic sequence in user-friendly formats. These formats assist user in the identification of promiscuous MHC binders in an antigen sequence that can bind to large number of alleles. ProPred1 also allows the prediction of the standard proteasome and immunoproteasome cleavage sites in an antigenic sequence. This server allows identification of MHC binders, who have the cleavage site at the C terminus. The simultaneous prediction of MHC binders and proteasome cleavage sites in an antigenic sequence leads to the identification of potential T-cell epitopes. AVAILABILITY: Server is available at http://www.imtech.res.in/raghava/propred1/. Mirror site of this server is available at http://bioinformatics.uams.edu/mirror/propred1/ Supplementary information: Matrices and document on server are available at http://www.imtech.res.in/raghava/propred1/page2.html
 
Publisher Oxford University Press
 
Date 2003-05-22
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://crdd.osdd.net/open/97/1/raghava2003.pdf
Singh, Harpreet and Raghava, G.P.S. (2003) ProPred1: prediction of promiscuous MHC Class-I binding sites. Bioinformatics (Oxford, England), 19 (8). pp. 1009-14. ISSN 1367-4803
 
Relation http://bioinformatics.oxfordjournals.org/content/19/8/1009.long
http://crdd.osdd.net/open/97/