Record Details

Pcleavage: an SVM based method for prediction of constitutive proteasome and immunoproteasome cleavage sites in antigenic sequences.

DIR@IMTECH: CSIR-Institute of Microbial Technology

View Archive Info
 
 
Field Value
 
Title Pcleavage: an SVM based method for prediction of constitutive proteasome and immunoproteasome cleavage sites in antigenic sequences.
 
Creator Bhasin, Manoj
Raghava, G.P.S.
 
Subject QR Microbiology
 
Description This manuscript describes a support vector machine based method for the prediction of constitutive as well as immunoproteasome cleavage sites in antigenic sequences. This method achieved Matthew's correlation coefficents of 0.54 and 0.43 on in vitro and major histocompatibility complex ligand data, respectively. This shows that the performance of our method is comparable to that of the NetChop method, which is currently considered to be the best method for proteasome cleavage site prediction. Based on the method, a web server, Pcleavage, has also been developed. This server accepts protein sequences in any standard format and present results in a user-friendly format. The server is available for free use by all academic users at the URL http://www.imtech.res.in/raghava/pcleavage/ or http://bioinformatics.uams.edu/mirror/pcleavage/.
 
Publisher Oxford University Press
 
Date 2005-07-01
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://crdd.osdd.net/open/170/1/raghava2005.5.pdf
Bhasin, Manoj and Raghava, G.P.S. (2005) Pcleavage: an SVM based method for prediction of constitutive proteasome and immunoproteasome cleavage sites in antigenic sequences. Nucleic acids research, 33 (Web Se). W202-7. ISSN 1362-4962
 
Relation http://nar.oxfordjournals.org/content/33/suppl_2/W202.full-text-lowres.pdf
http://crdd.osdd.net/open/170/