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Neural network designs for poly-beta-hydroxybutyrate production optimization under simulated industrial conditions.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Neural network designs for poly-beta-hydroxybutyrate production optimization under simulated industrial conditions.
 
Creator Patnaik, P R
 
Subject QR Microbiology
 
Description Improvement of the fermentation efficiency of poly-beta-hydroxybutyrate (PHB) may make it competitive with chemically synthesized petroleum-based polymers. One step toward this is optimization of fluid dispersion and the feed rates to a fed-batch bioreactor. In a recent study using a fermentation model, dispersion corresponding to a Peclet number of approximately 20 was shown to maximize the productivity of PHB. Here further improvement has been investigated using neural optimization. A comparison of seven neural topologies has shown that while feed-forward and radial basis neural networks are computationally efficient, recurrent networks generate higher concentrations of PHB. All networks enhanced the productivity by 16-93% over model-based optimization.
 
Publisher Springer Science
 
Date 2005-03
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://crdd.osdd.net/open/178/1/patnaik2005.pdf
Patnaik, P R (2005) Neural network designs for poly-beta-hydroxybutyrate production optimization under simulated industrial conditions. Biotechnology letters, 27 (6). pp. 409-15. ISSN 0141-5492
 
Relation http://www.springerlink.com/content/q06u276873843413/
http://crdd.osdd.net/open/178/