Record Details

Tuftsin-bearing liposomes as drug vehicles in the treatment of experimental aspergillosis.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Field Value
 
Title Tuftsin-bearing liposomes as drug vehicles in the treatment of experimental aspergillosis.
 
Creator Owais, M
Ahmed, I
Krishnakumar, B
Jain, R K
Bachhawat, B K
Gupta, C M
 
Subject QR Microbiology
 
Description Encapsulation of amphotericin B in tuftsin-bearing liposomes greatly increased its efficacy in treatment of human aspergillosis in mice. Also, the drug efficacy was significantly increased by pretreating the animals with drug-free tuftsin-bearing liposomes. These results demonstrate that macrophage activation can considerably enhance the therapeutic efficacy of antifungal drugs, like amphotericin B.
 
Publisher Elsevier Science
 
Date 1993-07-12
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://crdd.osdd.net/open/417/1/gupta93.pdf
Owais, M and Ahmed, I and Krishnakumar, B and Jain, R K and Bachhawat, B K and Gupta, C M (1993) Tuftsin-bearing liposomes as drug vehicles in the treatment of experimental aspergillosis. FEBS letters, 326 (1-3). pp. 56-8. ISSN 0014-5793
 
Relation http://www.sciencedirect.com/science/article/pii/001457939381760W#bCOR1
http://crdd.osdd.net/open/417/