Characterization of soluble rifamycin oxidase from Curvularia lunata var. aeria.
DIR@IMTECH: CSIR-Institute of Microbial Technology
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Title |
Characterization of soluble rifamycin oxidase from Curvularia lunata var. aeria.
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Creator |
Banerjee, U C
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Subject |
QR Microbiology
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Description |
Curvularia lunata var. aeria was grown on yeast extract, peptone and carboxymethylcellulose (YPC) medium for the production of extracellular rifamycin oxidase. The enzyme was partially purified through a Sephadex G-75 column. The half lives of rifamycin oxidase at 30 degrees and 40 degrees C were 9 d and 100 min, respectively. The activation and deactivation energies of the partially purified enzyme, calculated from Arrhenius plots, were 5.80 and 35.10 kcal mol-1, respectively. The enzyme exhibited a Km (rifamycin B) value of 0.67 mmol l-1 and a Vmax of 11 mumol h-1.ml. Three metal ions, Fe2+, Ag+ and Hg2+, inhibited the enzyme in the 10-20 mmol l-1 metal ion concentration range. Catalytic activity was not affected by the chelating agent, EDTA.
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Publisher |
Wiley/Blackwell Scientific Publications
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Date |
1993-07
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Identifier |
http://crdd.osdd.net/open/418/1/Banerjee1993%28S%29.pdf
Banerjee, U C (1993) Characterization of soluble rifamycin oxidase from Curvularia lunata var. aeria. Letters in applied microbiology, 17 (1). pp. 1-3. ISSN 0266-8254 |
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Relation |
http://onlinelibrary.wiley.com/doi/10.1111/lam.1993.17.issue-1/issuetoc
http://crdd.osdd.net/open/418/ |
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