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Biotransformations of rifamycins: process possibilities.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Field Value
 
Title Biotransformations of rifamycins: process possibilities.
 
Creator Banerjee, U C
Saxena, B
Chisti, Y.
 
Subject QD Chemistry
 
Description Rifampicin, an important antibiotic, is manufactured by chemical conversion of rifamycin S which is obtained by the chemical modification of rifamycin B. Rifamycin B is a product of Nocardia mediterranei fermentations. The chemical conversion of rifamycin B to rifamycin S has many disadvantages: Strong acidic conditions are required, heavy foam formation accompanies transformation and the yields are low. This review highlights the developments in alternative, biochemical transformations using enzymes and cells; the main focus is on transformations carried out by rifamycin oxidase.
 
Publisher Elsevier Science
 
Date 1992
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://crdd.osdd.net/open/425/1/banerjee92.pdf
Banerjee, U C and Saxena, B and Chisti, Y. (1992) Biotransformations of rifamycins: process possibilities. Biotechnology advances, 10 (4). pp. 577-95. ISSN 0734-9750
 
Relation http://www.sciencedirect.com/science/article/pii/073497509291454M
http://crdd.osdd.net/open/425/