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Signalling mechanisms in Mycobacteria.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Signalling mechanisms in Mycobacteria.
 
Creator Chakraborti, Pradip K
Matange, Nishad
Nandicoori, Vinay K
Singh, Yogendra
Tyagi, Jaya S
Visweswariah, Sandhya S
 
Subject R Medicine (General)
 
Description The importance of inter- and intracellular signal transduction in all forms of life cannot be underestimated. A large number of genes dedicated to cellular signalling are found in almost all sequenced genomes, and Mycobacteria are no exception. What appears to be interesting in Mycobacteria is that well characterized signalling mechanisms used by bacteria, such as the histidine-aspartate phosphorelay seen in two-component systems, are found alongside signalling components that closely mimic those seen in higher eukaryotes. This review will describe the important contribution made by researchers in India towards the identification and characterization of proteins involved in two-component signalling, protein phosphorylation and cyclic nucleotide metabolism.
 
Publisher Elsevier Science
 
Date 2011-09
 
Type Article
PeerReviewed
 
Relation http://www.sciencedirect.com/science/article/pii/S1472979211000680
http://crdd.osdd.net/open/467/
 
Identifier Chakraborti, Pradip K and Matange, Nishad and Nandicoori, Vinay K and Singh, Yogendra and Tyagi, Jaya S and Visweswariah, Sandhya S (2011) Signalling mechanisms in Mycobacteria. Tuberculosis (Edinburgh, Scotland), 91 (5). pp. 432-40. ISSN 1873-281X