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Zeta potential based colorimetric immunoassay for the direct detection of diabetic marker HbA1c using gold nanoprobes.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Zeta potential based colorimetric immunoassay for the direct detection of diabetic marker HbA1c using gold nanoprobes.
 
Creator Wangoo, Nishima
Kaushal, Jyotsna
Bhasin, K K
Mehta, S K
Suri, C Raman
 
Subject QD Chemistry
 
Description A one-step homogeneous colorimetric immunoassay format coupled with zeta potential measurements for determination of specific diabetic biomarker glycated hemoglobin (HbA1c) using functionalised gold nanoparticles as bioprobes is reported. The assay exhibited an excellent sensitivity based on absorbance and zeta potential measurements showing the dynamic response range from 0.001-0.004 mg mL(-1) for HbA1c with a detection limit of 0.0015 mg mL(-1).
 
Publisher RSC Publishing
 
Date 2010-08-21
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://crdd.osdd.net/open/511/1/suri10.1.pdf
Wangoo, Nishima and Kaushal, Jyotsna and Bhasin, K K and Mehta, S K and Suri, C Raman (2010) Zeta potential based colorimetric immunoassay for the direct detection of diabetic marker HbA1c using gold nanoprobes. Chemical communications (Cambridge, England), 46 (31). pp. 5755-7. ISSN 1364-548X
 
Relation http://pubs.rsc.org/en/content/articlepdf/2010/cc/c0cc00224k
http://crdd.osdd.net/open/511/