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Regulation of alpha- and beta-tubulin mRNAs in rat brain during synaptogenesis.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Regulation of alpha- and beta-tubulin mRNAs in rat brain during synaptogenesis.
 
Creator Bhattacharya, B
Mandal, C
Basu, S
Sarkar, P K
 
Subject QR Microbiology
 
Description Developmental alterations in alpha- and beta-tubulin mRNA in polysomes from brains of -3 days (fetal) to 30-day-old rats were quantitated by using well-characterized chicken alpha- and beta-tubulin cDNA probes, pT1 and pT2 having 80-90% homology with rat sequences. Northern blot analysis revealed a single major (greater than 95%) 1.8 kb mRNA for both alpha- and beta-tubulin. Quantitation by slot hybridization indicates a virtually coordinate expression of alpha- and beta-tubulin mRNA with a maximal level around day 5 after birth, which represents the mid-phase of synaptogenesis.
 
Publisher Elsevier Science
 
Date 1987-07
 
Type Article
PeerReviewed
 
Relation http://www.sciencedirect.com/science/article/pii/0169328X8790009X
http://crdd.osdd.net/open/641/
 
Identifier Bhattacharya, B and Mandal, C and Basu, S and Sarkar, P K (1987) Regulation of alpha- and beta-tubulin mRNAs in rat brain during synaptogenesis. Brain research, 388 (2). pp. 159-62. ISSN 0006-8993