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The Effect Of Macromixing On Oscillatory Behavior In Recombinant Fermentation In A Continuous Stirred Tank Reactor.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title The Effect Of Macromixing On Oscillatory Behavior In Recombinant Fermentation In A Continuous Stirred Tank Reactor.
 
Creator PATNAIK, P.R.
 
Subject QR Microbiology
 
Description A general model is presented for recombinant fermentation in a chemostat in which micromixing may be imperfect. Using the production of tryptophan synthetase as an example and the dilution rate, D, as the bifurcation parameter, conditions are first derived for Hopf bifurcation in a perfectly mixed chemostat. The bifurcation surfaces in three-dimensional space are such that oscillatory solutions exist above the surfaces and washout conditions below. A similar analysis is done for imperfect mixing. The bifurcation region is a concave hyperboloid in the [D,f, n]-space, where f and n ; are model parameters. It is argued that poor macromixing reduces the range of D over which bifurcation to periodic solutions is possible.
 
Publisher Taylor and francis group
 
Date 1993
 
Type Article
PeerReviewed
 
Relation http://dx.doi.org/10.1080/00986449308936200
http://crdd.osdd.net/open/679/
 
Identifier PATNAIK, P.R. (1993) The Effect Of Macromixing On Oscillatory Behavior In Recombinant Fermentation In A Continuous Stirred Tank Reactor. Chemical Engineering Communications, 125 (1). pp. 155-169. ISSN 0098-6445