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ACPR, a STE12 homologue from Candida albicans, is a strong inducer of pseudohyphae in Saccharomyces cerevisiae haploids and diploids.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title ACPR, a STE12 homologue from Candida albicans, is a strong inducer of pseudohyphae in Saccharomyces cerevisiae haploids and diploids.
 
Creator Singh, P
Ganesan, K
Malathi, K
Ghosh, D
Datta, A
 
Subject QD Chemistry
 
Description ACPR from Candida albicans encodes a protein antigenically related to the secretory acid proteinase of this yeast. Its amino terminal domain is highly similar to the amino terminal, DNA-binding domain of STE12 of Saccharomyces cerevisiae. STE12 is involved in mating of haploids and in pseudohyphae formation in diploids. ACPR, or its DNA-binding domain swapped into STE12, can support pseudohyphae formation in S. cerevisiae diploids. However, unlike STE12, these constructs affect the budding pattern and induce pseudohyphae formation in S. cerevisiae haploids as well, and this induction is independent of the nitrogen status of the medium. ACPR appears to be a stronger inducer of pseudohyphae than STE12 and is likely to be involved in the formation of pseudohyphae and hyphae in C. albicans.
 
Publisher Elsevier Science/Academic Press
 
Date 1994-12-15
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://crdd.osdd.net/open/704/1/datta1994.pdf
Singh, P and Ganesan, K and Malathi, K and Ghosh, D and Datta, A (1994) ACPR, a STE12 homologue from Candida albicans, is a strong inducer of pseudohyphae in Saccharomyces cerevisiae haploids and diploids. Biochemical and biophysical research communications, 205 (2). pp. 1079-85. ISSN 0006-291X
 
Relation http://www.sciencedirect.com/science/article/pii/S0006291X84727768
http://crdd.osdd.net/open/704/