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Biodegradation of p-nitrophenol via 1,2,4-benzenetriol by an Arthrobacter sp.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Biodegradation of p-nitrophenol via 1,2,4-benzenetriol by an Arthrobacter sp.
 
Creator Jain, R K
Dreisbach, J H
Spain, J C
 
Subject QR Microbiology
 
Description The degradation of p-nitrophenol (PNP) by Moraxella and Pseudomonas spp. involves an initial monooxygenase-catalyzed removal of the nitro group. The resultant hydroquinone is subject to ring fission catalyzed by a dioxygenase enzyme. We have isolated a strain of an Arthrobacter sp., JS443, capable of degrading PNP with stoichiometric release of nitrite. During induction of the enzymes required for growth on PNP, 1,2,4-benzenetriol was identified as an intermediate by gas chromatography-mass spectroscopy (GC-MS) and radiotracer studies. 1,2,4-Benzenetriol was converted to maleylacetic acid, which was further degraded by the beta-ketoadipate pathway. Conversion of PNP to 1,2,4-benzenetriol is catalyzed by a monooxygenase system in strain JS443 through the formation of 4-nitrocatechol, 4-nitroresorcinol, or both. Our results clearly indicate the existence of an alternative pathway for the biodegradation of PNP.
 
Publisher ASM
 
Date 1994-08
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://crdd.osdd.net/open/709/1/jain1994.pdf
Jain, R K and Dreisbach, J H and Spain, J C (1994) Biodegradation of p-nitrophenol via 1,2,4-benzenetriol by an Arthrobacter sp. Applied and environmental microbiology, 60 (8). pp. 3030-2. ISSN 0099-2240
 
Relation http://aem.asm.org/content/60/8/3030.abstract
http://crdd.osdd.net/open/709/