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Neural simulation of an unsteady state continuous recombinant fermentation with imperfect mixing.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Neural simulation of an unsteady state continuous recombinant fermentation with imperfect mixing.
 
Creator Patnaik, P R
 
Subject QR Microbiology
 
Description A continuous fermentation based on a recombinant Escherichia coli strain producing tryptophan synthetase has been simulated by a back-propagation neural network. Data for the network were generated through known kinetics applied to a reactor model with an adjustable degree of macromixing of the broth. A network with just one hidden layer performed satisfactorily for both poor and good macromixing. The best performance was at an intermediate level of mixing, in the region of maximum productivity of the recombinant protein.
 
Publisher Springer Science
 
Date 1996
 
Type Article
PeerReviewed
 
Relation http://dx.doi.org/10.1007/BF00157364
http://crdd.osdd.net/open/744/
 
Identifier Patnaik, P R (1996) Neural simulation of an unsteady state continuous recombinant fermentation with imperfect mixing. Biotechnology Techniques, 10 (8). pp. 573-578. ISSN 0951-208X