ICAR Research Data Repository for Knowledge Management
Spectral analysis of the effect of inflow noise on a fed-batch fermentation for recombinant β-galactosidase
DIR@IMTECH: CSIR-Institute of Microbial Technology
View Archive Info| Field | Value | |
| Title |
Spectral analysis of the effect of inflow noise on a fed-batch fermentation for recombinant β-galactosidase
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| Creator |
Patnaik, P R
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| Subject |
QR Microbiology
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| Description |
The fermentative production of β-galactosidase from Escherichia coli CSH50 containing the plasmid pOU140 is mechanistically complex and difficult to model in a nonideal bioreactor. A spectral analysis has been done for a fed-batch fermentation with Gaussian disturbances in the feed stream. Inflow noise converts a smooth operation into aperiodic motion, as observed in some chemical reactions also. The disturbances also cause significant differences in the frequency responses of intra-cellular (plasmid DNA and β-galactosidase) and extra-cellular (concentration and mass fraction of recombinant cells) variables, whose implications are discussed.
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| Publisher |
Springer Science
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| Date |
1997
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://crdd.osdd.net/open/763/1/patnaik1997.pdf
Patnaik, P R (1997) Spectral analysis of the effect of inflow noise on a fed-batch fermentation for recombinant β-galactosidase. Bioprocess Engineering, 17 (2). p. 93. ISSN 0178515X |
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| Relation |
http://dx.doi.org/10.1007/s004490050359
http://crdd.osdd.net/open/763/ |
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