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Impact of field vaccination with a Theileria annulata schizont cell culture vaccine on the epidemiology of tropical theileriosis

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Impact of field vaccination with a Theileria annulata schizont cell culture vaccine on the epidemiology of tropical theileriosis
 
Creator Singh, S.
Khatri, Neeraj
Manuja, A.
Sharma, R.D.
Malhotra, D.V.
Nichani, A.K.
 
Subject RZ Other systems of medicine
 
Description Tropical theileriosis, caused by Theileria annulata, is an important tick-borne disease of cattle. A cell culture attenuated vaccine has been developed in our laboratory by long-term in vitro propagation of the schizont stage of the parasite. A longitudinal study was conducted at selected farms housing indigenous, cross-bred and exotic animals to investigate the effect of vaccination on the epidemiology of the disease. A total of 120 animals in 4 age groups were vaccinated with the vaccine before the onset of disease season. An equal number of age-matched animals were kept as controls at the same sites. Animals were monitored for 14 months at monthly intervals. The 97.5% vaccinated animals showed a rise in antibody titres 1 month post-vaccination, as determined by single dilution ELISA. The 78.3% of non-vaccinated animals became sero-positive over the period of observation. Mean antibody titres were significantly higher in vaccinated than non-vaccinated animals. Cross-bred animals showed higher antibody titres followed by exotic and indigenous animals in both the vaccinated and non-vaccinated groups. However, the antibody titres in animals of different ages were similar. The 36.7% vaccinated and 64.2% non-vaccinated animals became carriers (
 
Publisher Elsevier Science
 
Date 2001
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://crdd.osdd.net/open/856/1/neeraj2001.1.pdf
Singh, S. and Khatri, Neeraj and Manuja, A. and Sharma, R.D. and Malhotra, D.V. and Nichani, A.K. (2001) Impact of field vaccination with a Theileria annulata schizont cell culture vaccine on the epidemiology of tropical theileriosis. Veterinary Parasitology, 101 (2). pp. 91-100. ISSN 03044017
 
Relation http://dx.doi.org/10.1016/S0304-4017(01)00502-7
http://crdd.osdd.net/open/856/