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Effect of oxygen transfer on glycerol biosynthesis by an osmophilic yeast Candida magnoliae I(2)B.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Effect of oxygen transfer on glycerol biosynthesis by an osmophilic yeast Candida magnoliae I(2)B.
 
Creator Sahoo, Debendra K
Agarwal, Gopal P
 
Subject QR Microbiology
 
Description The influence of oxygen on glycerol production by an osmophilic yeast, Candida magnoliae I(2)B, was studied in a bioreactor. Oxygen transfer rates (OTRs) and volumetric oxygen transfer coefficients (k(L)a) were determined at different aeration and agitation rates. Cell growth as well as glycerol production was strongly affected by oxygen supply. Improvement in OTRs resulted in increased cell growth and glycerol yield. However, at high OTRs, there was a reduction in glucose uptake rate, indicating Pasteur Effect, and glycerol accumulation was also reduced at k(L)a of 253 h(-1). The availability of oxygen per unit of cell mass was found to be the most important factor that controlled cell growth, glucose uptake, and glycerol yield. The overall productivity and yield of glycerol could be related with k(L)a. The biosynthesis of glycerol was found to both growth- and non-growth-associated, although glycerol was mainly produced in post-exponential phase.
 
Publisher wiley
 
Date 2002-06-05
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://crdd.osdd.net/open/899/1/sahoo2002.pdf
Sahoo, Debendra K and Agarwal, Gopal P (2002) Effect of oxygen transfer on glycerol biosynthesis by an osmophilic yeast Candida magnoliae I(2)B. Biotechnology and bioengineering, 78 (5). pp. 545-55. ISSN 0006-3592
 
Relation http://onlinelibrary.wiley.com/doi/10.1002/bit.10237/pdf
http://crdd.osdd.net/open/899/