Record Details

Mixing control as a device to increase PHB production in batch fermentations with co-cultures of Lactobacillus delbrueckii and Ralstonia eutropha

DIR@IMTECH: CSIR-Institute of Microbial Technology

View Archive Info
 
 
Field Value
 
Title Mixing control as a device to increase PHB production in batch fermentations with co-cultures of Lactobacillus delbrueckii and Ralstonia eutropha
 
Creator Ganduri, V.S.R.K.
Ghosh, S
Patnaik, P R
 
Subject QD Chemistry
 
Description Poly(β-hydroxybutyric acid) or PHB is a bacterial polymer whose biocompatability, biodegradability and versatile properties make it an eco-friendly substitute for synthetic polymers. It is synthesized by Ralstonia eutropha from glucose as the main carbon source. However, better productivity is obtained through co-cultures of Lactobacillus delbrueckii and R. eutropha. PHB concentrations of 12 g/l have been reported in laboratory experiments and up to 40 g/l are theoretically achievable by fed-batch fermentation with programmable control of carbon and nitrogen feed rates. In this analysis, it is shown that equally high yields are possible in simpler batch fermentations by controlling the mixing intensity. Since mixing in large bioreactors is inherently incomplete, the present approach allows this nonideal feature to be gainfully utilized.
 
Publisher Elsevier Science
 
Date 2005
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://crdd.osdd.net/open/999/1/patnaik2005.3.pdf
Ganduri, V.S.R.K. and Ghosh, S and Patnaik, P R (2005) Mixing control as a device to increase PHB production in batch fermentations with co-cultures of Lactobacillus delbrueckii and Ralstonia eutropha. Process Biochemistry, 40 (1). pp. 257-264. ISSN 13595113
 
Relation http://dx.doi.org/10.1016/j.procbio.2004.01.012
http://crdd.osdd.net/open/999/