Enantiocomplementary reduction of 3-phenylthiopropan-2-one by Bacillus sp.: effect of medium components.
DIR@IMTECH: CSIR-Institute of Microbial Technology
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Title |
Enantiocomplementary reduction of 3-phenylthiopropan-2-one by Bacillus sp.: effect of medium components.
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Creator |
Rampal, Poonam
Saini, H S Raj, Mayil Chimni, Swapandeep Singh Chadha, Bhupinder Singh |
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Subject |
QR Microbiology
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Description |
The enantioselectivity of the enzymes responsible for reduction of prochiral compound 3-phenylthiopropan-2-one was dependent on the concentration of yeast extract and glucose in the growth medium. Low concentrations of yeast extract (0.1-0.9% w/v) favored the formation of S-enantiomer (62% ee at 0.1% w/v yeast extract) of 3-phenylthiopropan-2-ol. However, R-enantiomer of the reduced product was formed when MSM was supplemented with yeast extract at a concentration of 1% (w/v) or more with a maximum ee of 85% at 2.0% (w/v) yeast extract supplement in the growth medium.
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Publisher |
Elsevier Science
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Date |
2007-02
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Identifier |
http://crdd.osdd.net/open/1021/1/mayilraj2006.pdf
Rampal, Poonam and Saini, H S and Raj, Mayil and Chimni, Swapandeep Singh and Chadha, Bhupinder Singh (2007) Enantiocomplementary reduction of 3-phenylthiopropan-2-one by Bacillus sp.: effect of medium components. Bioresource technology, 98 (3). pp. 725-8. ISSN 0960-8524 |
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Relation |
http://www.sciencedirect.com/science/article/pii/S0960852406000514
http://crdd.osdd.net/open/1021/ |
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