Stem bromelain-induced macrophage apoptosis and activation curtail Mycobacterium tuberculosis persistence.
DIR@IMTECH: CSIR-Institute of Microbial Technology
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Title |
Stem bromelain-induced macrophage apoptosis and activation curtail Mycobacterium tuberculosis persistence.
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Creator |
Mahajan, Sahil
Chandra, Vemika Dave, Sandeep Nanduri, Ravikanth Gupta, Pawan |
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Subject |
R Medicine (General)
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Description |
Mycobacterium tuberculosis, the causative agent of tuberculosis, has a remarkable ability to usurp its host's innate immune response, killing millions of infected people annually. One approach to manage infection is prevention through the use of natural agents. In this regard, stem bromelain (SBM), a pharmacologically active member of the sulfhydryl proteolytic enzyme family, obtained from Ananas comosus and possessing a remarkable ability to induce the innate and acquired immune systems, is important.
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Publisher |
Oxford University Press
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Date |
2012-08-01
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Type |
Article
PeerReviewed |
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Relation |
http://jid.oxfordjournals.org/content/206/3/366.full.pdf+html
http://crdd.osdd.net/open/1248/ |
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Identifier |
Mahajan, Sahil and Chandra, Vemika and Dave, Sandeep and Nanduri, Ravikanth and Gupta, Pawan (2012) Stem bromelain-induced macrophage apoptosis and activation curtail Mycobacterium tuberculosis persistence. The Journal of infectious diseases, 206 (3). pp. 366-76. ISSN 1537-6613
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