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Role of the two component signal transduction system CpxAR in conferring cefepime and chloramphenicol resistance in Klebsiella pneumoniae NTUH-K2044.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Role of the two component signal transduction system CpxAR in conferring cefepime and chloramphenicol resistance in Klebsiella pneumoniae NTUH-K2044.
 
Creator Srinivasan, Vijaya Bharathi
Vaidyanathan, Vasanth
Mondal, Amitabha
Rajamohan, Govindan
 
Subject QR Microbiology
 
Description Klebsiella pneumoniae is a gram-negative, non-motile, facultative anaerobe belonging to the Enterobacteriaceae family of the γ-Proteobacteria class in the phylum Proteobacteria. Multidrug resistant K. pneumoniae have caused major therapeutic problems worldwide due to emergence of extended-spectrum β-lactamase producing strains. Two-component systems serve as a basic stimulus-response coupling mechanism to allow organisms to sense and respond to changes in many different environmental conditions including antibiotic stress.
 
Publisher PLOS One
 
Date 2012
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://crdd.osdd.net/open/1254/1/rajmohan2012.pdf
Srinivasan, Vijaya Bharathi and Vaidyanathan, Vasanth and Mondal, Amitabha and Rajamohan, Govindan (2012) Role of the two component signal transduction system CpxAR in conferring cefepime and chloramphenicol resistance in Klebsiella pneumoniae NTUH-K2044. PloS one, 7 (4). e33777. ISSN 1932-6203
 
Relation http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0033777
http://crdd.osdd.net/open/1254/