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In silico approaches for designing highly effective cell penetrating peptides.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title In silico approaches for designing highly effective cell penetrating peptides.
 
Creator Gautam, Ankur
Chaudhary, Kumardeep
Kumar, Rahul
Sharma, Arun
Kapoor, Pallavi
Tyagi, Atul
Raghava, G.P.S.
 
Subject QR Microbiology
 
Description Cell penetrating peptides have gained much recognition as a versatile transport vehicle for the intracellular delivery of wide range of cargoes (i.e. oligonucelotides, small molecules, proteins, etc.), that otherwise lack bioavailability, thus offering great potential as future therapeutics. Keeping in mind the therapeutic importance of these peptides, we have developed in silico methods for the prediction of cell penetrating peptides, which can be used for rapid screening of such peptides prior to their synthesis.
 
Publisher BioMedCentral
 
Date 2013
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://crdd.osdd.net/open/1303/1/Raghava2013.pdf
Gautam, Ankur and Chaudhary, Kumardeep and Kumar, Rahul and Sharma, Arun and Kapoor, Pallavi and Tyagi, Atul and Raghava, G.P.S. (2013) In silico approaches for designing highly effective cell penetrating peptides. Journal of translational medicine, 11. p. 74. ISSN 1479-5876
 
Relation http://www.translational-medicine.com/content/11/1/74
http://crdd.osdd.net/open/1303/