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Designing of inhibitors against drug tolerant Mycobacterium tuberculosis (H37Rv).

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Designing of inhibitors against drug tolerant Mycobacterium tuberculosis (H37Rv).
 
Creator Singla, Deepak
Tewari, Rupinder
Kumar, Ashwani
Raghava, G.P.S.
 
Subject QR Microbiology
 
Description Mycobacterium tuberculosis (M.tb) is the causative agent of tuberculosis, killing ~1.7 million people annually. The remarkable capacity of this pathogen to escape the host immune system for decades and then to cause active tuberculosis disease, makes M.tb a successful pathogen. Currently available anti-mycobacterial therapy has poor compliance due to requirement of prolonged treatment resulting in accelerated emergence of drug resistant strains. Hence, there is an urgent need to identify new chemical entities with novel mechanism of action and potent activity against the drug resistant strains.
 
Publisher BioMedCentral
 
Date 2013
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://crdd.osdd.net/open/1304/1/raghava2013.1.pdf
Singla, Deepak and Tewari, Rupinder and Kumar, Ashwani and Raghava, G.P.S. (2013) Designing of inhibitors against drug tolerant Mycobacterium tuberculosis (H37Rv). Chemistry Central journal, 7 (1). p. 49. ISSN 1752-153X
 
Relation http://journal.chemistrycentral.com/content/7/1/49
http://crdd.osdd.net/open/1304/