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Evidence of a new metabolic capacity in an emerging diarrheal pathogen: lessons from the draft genomes of Vibrio fluvialis strains PG41 and I21563

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Evidence of a new metabolic capacity in an emerging diarrheal pathogen: lessons from the draft genomes of Vibrio fluvialis strains PG41 and I21563
 
Creator Khatri, Indu
Mahajan, Sakshi
Dureja, Chetna
Subramanian, Srikrishna
Raychaudhuri, Saumya
 
Subject QR Microbiology
 
Description Background

Vibrio fluvialis is an emerging diarrheal pathogen for which no genome is currently available. In this work, draft genomes of two closely related clinical strains PG41 and I21563 have been explored.
Results

V. fluvialis strains PG41 and I21563 were sequenced on the Illumina HiSeq 1000 platform to obtain draft genomes of 5.3 Mbp and 4.4 Mbp respectively. Our genome data reveal the presence of genes involved in ethanolamine utilization, which is further experimentally confirmed by growth analysis.
Conclusions

Combined in silico and growth analysis establish a new metabolic capacity of V. fluvialis to harvest energy from ethanolamine.
 
Publisher BioMedCentral
 
Date 2013
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://crdd.osdd.net/open/1309/1/Raychaudhari2013.pdf
Khatri, Indu and Mahajan, Sakshi and Dureja, Chetna and Subramanian, Srikrishna and Raychaudhuri, Saumya (2013) Evidence of a new metabolic capacity in an emerging diarrheal pathogen: lessons from the draft genomes of Vibrio fluvialis strains PG41 and I21563. Gut Pathogens, 5 (1). p. 20. ISSN 1757-4749
 
Relation http://dx.doi.org/10.1186/1757-4749-5-20
http://crdd.osdd.net/open/1309/