ICAR Research Data Repository for Knowledge Management
Nanobioprobe mediated DNA aptamers for explosive detection.
DIR@IMTECH: CSIR-Institute of Microbial Technology
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| Title |
Nanobioprobe mediated DNA aptamers for explosive detection.
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| Creator |
Priyanka,
Shorie, Munish Bhalla, Vijayender Pathania, Preeti Suri, C Raman |
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| Description |
Specific nucleic acid aptamers using the microtiter plate based modified SELEX method against explosive trinitrotoluene are reported. Efficient partitioning of dsDNA was carried out using streptavidin labeled gold nanoprobes for the selection of specific aptamers. The selected binders having an affinity of ~10(-7) M were used in the newly developed electrochemical aptasensor, exhibiting a detection limit of around 1 ppb for trinitrotoluene.
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| Publisher |
Cambridge : Royal Society of Chemistry
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| Date |
2014-02-04
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| Type |
Article
PeerReviewed |
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| Relation |
http://pubs.rsc.org/en/Content/ArticleLanding/2014/CC/c3cc47562j#!divAbstract
http://crdd.osdd.net/open/1533/ |
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| Identifier |
Priyanka, and Shorie, Munish and Bhalla, Vijayender and Pathania, Preeti and Suri, C Raman (2014) Nanobioprobe mediated DNA aptamers for explosive detection. Chemical communications (Cambridge, England), 50 (9). pp. 1080-2. ISSN 1364-548X
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