Record Details

Biofunctionalized rebar graphene (f-RG) for label-free detection of cardiac marker troponin I.

DIR@IMTECH: CSIR-Institute of Microbial Technology

View Archive Info
 
 
Field Value
 
Title Biofunctionalized rebar graphene (f-RG) for label-free detection of cardiac marker troponin I.
 
Creator Tuteja, Satish K
Sabherwal, Priyanka
Deep, Akash
Rastogi, Richa
Paul, Ashok K
Suri, C Raman
 
Description One-step microwave-assisted unscrolling of carbon nanotubes to form functionalized rebar graphene (f-RG) is reported. The well-characterized f-RG on an interdigitated electrode biochip in a FET configuration showed enhanced electronic properties, as demonstrated with I-V characteristics. The developed device was biofunctionalized with specific anti-cTnI antibodies exhibiting a shift of threshold voltage from -2.15 V to -0.5 V and decrease in electron mobility from 3.609 × 10(4) to 8.877 × 10(3) cm(2) V(-1) s(-1). The new sensing strategy holds great promise for its applicability in diagnostics exhibiting high sensitivity (∼ 1 pg/mL) and specificity toward cardiac marker (cTnI).
 
Publisher Washington, D.C. : American Chemical Society
 
Date 2014-09-10
 
Type Article
PeerReviewed
 
Relation http://pubs.acs.org/doi/abs/10.1021/am503524e
http://crdd.osdd.net/open/1536/
 
Identifier Tuteja, Satish K and Sabherwal, Priyanka and Deep, Akash and Rastogi, Richa and Paul, Ashok K and Suri, C Raman (2014) Biofunctionalized rebar graphene (f-RG) for label-free detection of cardiac marker troponin I. ACS applied materials & interfaces, 6 (17). pp. 14767-71. ISSN 1944-8252