Sub-MICs of Carum copticum and Thymus vulgaris influence virulence factors and biofilm formation in Candida spp.
DIR@IMTECH: CSIR-Institute of Microbial Technology
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Title |
Sub-MICs of Carum copticum and Thymus vulgaris influence virulence factors and biofilm formation in Candida spp.
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Creator |
Khan, Mohd S A
Ahmad, Iqbal Cameotra, Swaranjit Singh Botha, Francien |
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Description |
Emergence of drug-resistant strains of Candida and inefficiency of conventional antifungal therapy has necessitated the search for alternative and new antifungal agents. Inhibition of virulence and biofilm are the potential drug targets. In this study, the oils of Carum copticum, Thymus vulgaris and their major active compound thymol as revealed by Gas chromatography and gas chromatography-mass spectrometry (GC-GC/MS) analysis were tested for their inhibitory activity against growth to determine sub-MIC values against 27 drug-resistant strains of Candida spp.
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Publisher |
London : BioMed Central, [2001-
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Date |
2014
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Type |
Article
PeerReviewed |
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Relation |
http://www.biomedcentral.com/1472-6882/14/337
http://crdd.osdd.net/open/1589/ |
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Identifier |
Khan, Mohd S A and Ahmad, Iqbal and Cameotra, Swaranjit Singh and Botha, Francien (2014) Sub-MICs of Carum copticum and Thymus vulgaris influence virulence factors and biofilm formation in Candida spp. BMC complementary and alternative medicine, 14. p. 337. ISSN 1472-6882
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