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Bio-functionalized graphene-graphene oxide nanocomposite based electrochemical immunosensing.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Bio-functionalized graphene-graphene oxide nanocomposite based electrochemical immunosensing.
 
Creator Sharma, Priyanka
Tuteja, Satish K
Bhalla, Vijayender
Shekhawat, G
Dravid, Vinayak P
Suri, C Raman
 
Description We report a novel in-situ electrochemical synthesis approach for the formation of functionalized graphene-graphene oxide (fG-GO) nanocomposite on screen-printed electrodes (SPE). Electrochemically controlled nanocomposite film formation was studied by transmission electron microscopy (TEM) and Raman spectroscopy. Further insight into the nanocomposite has been accomplished by the Fourier transformed infrared spectroscopy (FTIR), thermal gravimetric analysis (TGA) and X-ray diffraction (XRD) spectroscopy. Configured as a highly responsive screen-printed immunosensor, the fG-GO nanocomposite on SPE exhibits electrical and chemical synergies of the nano-hybrid functional construct by combining good electronic properties of functionalized graphene (fG) and the facile chemical functionality of graphene oxide (GO) for compatible bio-interface development using specific anti-diuron antibody. The enhanced electrical properties of nanocomposite biofilm demonstrated a significant increase in electrochemical signal response in a competitive inhibition immunoassay format for diuron detection, promising its potential applicability for ultra-sensitive detection of range of target analytes.
 
Publisher Oxford : Elsevier Advanced Technology
 
Date 2013-01-15
 
Type Article
PeerReviewed
 
Relation http://www.sciencedirect.com/science/article/pii/S0956566312004204
http://crdd.osdd.net/open/1599/
 
Identifier Sharma, Priyanka and Tuteja, Satish K and Bhalla, Vijayender and Shekhawat, G and Dravid, Vinayak P and Suri, C Raman (2013) Bio-functionalized graphene-graphene oxide nanocomposite based electrochemical immunosensing. Biosensors & bioelectronics, 39 (1). pp. 99-105. ISSN 1873-4235