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Genome sequence, comparative analysis, and evolutionary insights into chitinases of entomopathogenic fungus Hirsutella thompsonii.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Genome sequence, comparative analysis, and evolutionary insights into chitinases of entomopathogenic fungus Hirsutella thompsonii.
 
Creator Agrawal, Yamini
Khatri, Indu
Subramanian, Srikrishna
Shenoy,, Belle Damodara
 
Subject QR Microbiology
 
Description Hirsutella thompsonii (Ht) is a fungal pathogen of acarines and the primary cause of epizootics among mites. The draft genomes of two isolates of Ht (MTCC 3556: Ht3, 34.6 Mb and MTCC 6686: Ht6, 34.7 Mb) are presented and compared with the genomes of Beauveria bassiana (Bb) ARSEF 2860 and Ophiocordyceps sinensis (Os) CO18. Comparative analysis of carbohydrate active enzymes, pathogen-host interaction genes, metabolism-associated genes, and genes involved in biosynthesis of secondary metabolites in the four genomes was carried out. Reduction in gene family sizes in Ht3 and Os as compared with Ht6 and Bb is observed. Analysis of the mating type genes in Ht reveals the presence of MAT idiomorphs which is suggestive of cryptic sexual traits in Ht. We further identify and classify putative chitinases that may function as virulence factors in fungal entomopathogens due to their role in degradation of arthropod cuticle.
 
Publisher Oxford University Press
 
Date 2015-03
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://crdd.osdd.net/open/1660/1/Subramanian%20S.%202015%20Genome%20Biol%20Evol-2015-Agrawal-916-30.pdf
Agrawal, Yamini and Khatri, Indu and Subramanian, Srikrishna and Shenoy,, Belle Damodara (2015) Genome sequence, comparative analysis, and evolutionary insights into chitinases of entomopathogenic fungus Hirsutella thompsonii. Genome biology and evolution, 7 (3). pp. 916-30. ISSN 1759-6653
 
Relation http://gbe.oxfordjournals.org/content/7/3/916/suppl/DC1
http://crdd.osdd.net/open/1660/