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Gambogic acid induced oxidative stress dependent caspase activation regulates both apoptosis and autophagy by targeting various key molecules (NF-κB, Beclin-1, p62 and NBR1) in human bladder cancer cells.
DIR@IMTECH: CSIR-Institute of Microbial Technology
View Archive Info| Field | Value | |
| Title |
Gambogic acid induced oxidative stress dependent caspase activation regulates both apoptosis and autophagy by targeting various key molecules (NF-κB, Beclin-1, p62 and NBR1) in human bladder cancer cells.
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| Creator |
Ishaq, Mohammad
Khan, Mohammad Aslam Sharma, Kapil Sharma, Gaurav Dutta, Rajesh Kumar Majumdar, Sekhar |
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| Subject |
QR Microbiology
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| Description |
Gambogic acid is a potent anticancer agent and has been found effective against various types of cancer cells. The present study was addressed to explore the cytotoxic potential of Gambogic acid and the modulation of autophagy and apoptosis in bladder cancer cells T24 and UMUC3.
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| Publisher |
Elsevier Publisher
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| Date |
2014-12
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| Type |
Article
PeerReviewed |
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| Relation |
http://www.sciencedirect.com/science/article/pii/S0304416514003031
http://crdd.osdd.net/open/1676/ |
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| Identifier |
Ishaq, Mohammad and Khan, Mohammad Aslam and Sharma, Kapil and Sharma, Gaurav and Dutta, Rajesh Kumar and Majumdar, Sekhar (2014) Gambogic acid induced oxidative stress dependent caspase activation regulates both apoptosis and autophagy by targeting various key molecules (NF-κB, Beclin-1, p62 and NBR1) in human bladder cancer cells. Biochimica et biophysica acta, 1840 (12). pp. 3374-84. ISSN 0006-3002
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