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Computer-Aided Virtual Screening and Designing of Cell-Penetrating Peptides.

DIR@IMTECH: CSIR-Institute of Microbial Technology

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Title Computer-Aided Virtual Screening and Designing of Cell-Penetrating Peptides.
 
Creator Gautam, Ankur
Chaudhary, Kumardeep
Kumar, Rahul
Raghava, G.P.S.
 
Subject QR Microbiology
 
Description Cell-penetrating peptides (CPPs) have proven their potential as versatile drug delivery vehicles. Last decade has witnessed an unprecedented growth in CPP-based research, demonstrating the potential of CPPs as therapeutic candidates. In the past, many in silico algorithms have been developed for the prediction and screening of CPPs, which expedites the CPP-based research. In silico screening/prediction of CPPs followed by experimental validation seems to be a reliable, less time-consuming, and cost-effective approach. This chapter describes the prediction, screening, and designing of novel efficient CPPs using "CellPPD," an in silico tool.
 
Publisher Springer
 
Date 2015
 
Type Article
PeerReviewed
 
Relation http://download.springer.com/static/pdf/217/chp%253A10.1007%252F978-1-4939-2806-4_4.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Fprotocol%2F10.1007%2F978-1-4939-2806-4_4&token2=exp=1454040805~acl=%2Fstatic%2Fpdf%2F217%2Fchp%25253A10.1007%25252F978-1-493
http://crdd.osdd.net/open/1763/
 
Identifier Gautam, Ankur and Chaudhary, Kumardeep and Kumar, Rahul and Raghava, G.P.S. (2015) Computer-Aided Virtual Screening and Designing of Cell-Penetrating Peptides. Methods in molecular biology (Clifton, N.J.), 1324. pp. 59-69. ISSN 1940-6029