Record Details

A highly efficient designer cell for enantioselective reduction of ketones

DIR@IMTECH: CSIR-Institute of Microbial Technology

View Archive Info
 
 
Field Value
 
Title A highly efficient designer cell for enantioselective reduction of ketones
 
Creator Srivastava, Gautam
Pal, Mohan
Kaur, Suneet
Jolly, R S
 
Subject QD Chemistry
QR Microbiology
 
Description A designer cell, surf-crs-gdh, coexpressing carbonyl reductase (crs) and glucose dehydrogenase (gdh) on the cell surface has been constructed and its enzyme activities are compared with those of the corresponding cell, cyto-crs-gdh, coexpressing crs and gdh in cytosol. For various ketones, surf-crs-gdh exhibited 48- to 265-fold higher crs activity per unit protein compared to cyto-crs-gdh.
 
Publisher Royal Society of Chemistry
 
Date 2015
 
Type Article
PeerReviewed
 
Relation http://dx.doi.org/10.1039/C4CY01017E
http://crdd.osdd.net/open/1781/
 
Identifier Srivastava, Gautam and Pal, Mohan and Kaur, Suneet and Jolly, R S (2015) A highly efficient designer cell for enantioselective reduction of ketones. Catalysis Science & Technology, 5 (1). pp. 105-108. ISSN 2044-4753