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Dietary fenugreek (Trigonella foenum-graecum) seeds and garlic (Alliumsativum) alleviates oxidative stress in experimental myocardial infarction.

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Relation http://ir.cftri.com/13163/
http://dx.doi.org/10.1016/j.fshw.2017.04.001
 
Title Dietary fenugreek (Trigonella foenum-graecum) seeds and garlic (Alliumsativum) alleviates oxidative stress in experimental myocardial infarction.
 
Creator Mukthamba, P.
Srinivasan, K.
 
Subject 01 Dietary Fiber
30 Spices/Condiments
 
Description Soluble fiber-rich fenugreek seeds (Trigonella foenum-graecum) and garlic (Allium sativum) are understood to exert cholesterol-lowering andantioxidant effects. The cardioprotective influence of a combination of fenugreek seeds and garlic by their antioxidant influence was evaluatedin hypercholesterolemic rats administered isoproterenol. Wistar rats were maintained on high-cholesterol diet for 8 weeks along with dietaryinterventions of fenugreek (10%), garlic (2%) and their combination. Myocardial infarction was induced with isoproterenol injection. Increasedcirculatory troponin, disturbed activities of cardiac ATPases, increased serum iron and decreased ceruloplasmin confirmed myocardial infarction.Elevated lipid peroxides accompanied with reduced antioxidant molecules caused by isoproterenol and altered activities of antioxidant enzymes inserum and heart in induced myocardial necrosis were countered by dietary fenugreek, garlic, and fenugreek + garlic. Dietary fenugreek seeds andgarlic ameliorated
 
Date 2017
 
Type Article
PeerReviewed
 
Format pdf
 
Language en
 
Identifier http://ir.cftri.com/13163/1/Food%20Science%20and%20Human%20Wellness%206%20%282017%29%2077%E2%80%9387.pdf
Mukthamba, P. and Srinivasan, K. (2017) Dietary fenugreek (Trigonella foenum-graecum) seeds and garlic (Alliumsativum) alleviates oxidative stress in experimental myocardial infarction. Food Science and Human Wellness, 6. pp. 77-87.