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Comparative assessment of physico-chemical characteristics and fibril formation capacity of thermostable carp scales collagen.

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Relation http://ir.cftri.com/13353/
http://dx.doi.org/10.1016/j.msec.2016.08.047
 
Title Comparative assessment of physico-chemical characteristics and fibril
formation capacity of thermostable carp scales collagen.
 
Creator Gaurav Kumar, Pal
Suresh, P. V.
 
Subject 03 Proteins
Fish
 
Description Collagen and collagen fibers have been widely documented as a potential and competitive biomaterial for medical
applications. However, the searches for safe and realistic new collagen sources are still underway. Currently,
fishery by-products (scales), a promising collagen source are usually discarded. In the present study, in vitro
fibril-forming ability of the extracted fish scale collagen is reported. The aim of the investigation was to evaluate
the concomitant comparison of fibril-forming abilities and characteristics of acid and pepsin soluble collagens
fromthe scales of Indianmajor carp catla (Catla catla) and rohu (Labeo rohita). The extracted collagenswere characterized
as type I,with a total yield of 2.80–4.11% (w/w). Denaturation temperature determined for all collagens
were between 35.9 and 37.7 °C. All collagens exhibited high solubility in acidic pH and low NaCl concentrations.
SEMclarified the lyophilized collagens and their fibril-forming capacity. Amino acid content and radical scavenging
efficacy were also analyzed for the extracted collagen. The results revealed that extracted scale collagen from
a renewable biological source could be used as biomaterials in various sectors. It might be suitable for preparing
collagen gel for biomedical devices or as a scaffold for cell culture because of its high stability and fibril formation
capacity.
 
Date 2017
 
Type Article
PeerReviewed
 
Format pdf
 
Language en
 
Identifier http://ir.cftri.com/13353/1/Materials%20Science%20and%20Engineering%20C%20Volume%2070%2C%20Part%201%2C%201%20January%202017%2C%20Pages%2032-40.pdf
Gaurav Kumar, Pal and Suresh, P. V. (2017) Comparative assessment of physico-chemical characteristics and fibril formation capacity of thermostable carp scales collagen. Materials Science and Engineering C, 70. pp. 32-40.