Record Details

Skin prick test analysis reveals cross-sensitization to tomato profilin and grass pollen in nasobronchialallergic patients with history of tomato food allergy.

IR@CSIR-CFTRI

View Archive Info
 
 
Field Value
 
Relation http://ir.cftri.com/13427/
http://dx.doi.org/10.23822/EurAnnACI.1764-1489.27
 
Title Skin prick test analysis reveals cross-sensitization
to tomato profilin and grass pollen in nasobronchialallergic
patients with history of tomato food allergy.
 
Creator Hegde, V. L.
Mahesh, P. A.
Venkatesh, Y. P.
 
Subject 01 Allergy
03 Tomato
 
Description The association between grass pollen sensitization and food allergy to tomato is of great interest.
We report here, the first such study in Indian population.
We investigated 246 allergic rhinitis / asthma patients by diagnostic case history and skin
prick test (SPT); grass pollen mix, tomato extract and purified tomato profilin were used for
SPT. Tomato profilin was purified by affinity chromatography, and analyzed by HPLC (95%
purity) and SDS-PAGE (14 kDa).
We observed that 38% of the patients had sensitization to both grass pollen and tomato fruit,
of which 92% were sensitized to tomato profilin. Among patients with a history of food allergy
to tomato fruit, the association was more pronounced (66%).
Tomato profilin appears to be an important cross-sensitizing panallergen in respiratory allergic
patients in the Indian subcontinent.
 
Date 2018
 
Type Article
PeerReviewed
 
Format pdf
 
Language en
 
Identifier http://ir.cftri.com/13427/1/Eur%20Ann%20Allergy%20Clin%20Immunol%20Vol%2050%2C%20N%201%2C%2010-18%2C%202018.pdf
Hegde, V. L. and Mahesh, P. A. and Venkatesh, Y. P. (2018) Skin prick test analysis reveals cross-sensitization to tomato profilin and grass pollen in nasobronchialallergic patients with history of tomato food allergy. European Annals of Allergy and Clinical Immunology, 50 (1). pp. 10-18.