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Study on the levels of trace elements in mild and severe psoriasis

IR@CSIR-CFTRI

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Relation http://ir.cftri.com/9031/
http://www.sciencedirect.com/science/article/B6T57-4W3PT77-1/2/93b9c7c8f3f1b7fa2236310f26030291
http://dx.doi.org/10.1016/j.cca.2009.04.012
 
Title Study on the levels of trace elements in mild and severe psoriasis
 
Creator Basavaraj, K. H.
Darshan, M. S.
Shanmugavelu, P.
Rashmi, R.
Mhatre, A. Yuti
Dhanabal, S. P.
Rao, K. S. J.
 
Subject 17 Toxicology
 
Description Background Psoriasis is a chronic, recurrent skin disorder characterized histologically by cutaneous inflammation, increased epidermal proliferation, hyperkeratosis, angiogenesis, abnormal keratinization, shortened maturation time and parakeratosis. Data on the involvement of trace elements in the pathogenesis of psoriasis is limited.Methods The elements namely Na, K, Ca, P, S, Mg, Cu, Zn, and Fe were analyzed in the serum samples of mild and severe psoriasis patients with a control group using inductively coupled plasma-atomic emission spectroscopy (ICP-AES). Patients were assessed as per standard clinical diagnostic criteria and classified into mild and severe psoriasis groups using Psoriasis Area Severity Index (PASI) score.Results In mild psoriasis, the levels of K, P, Cu, and Mg were increased significantly (p
 
Date 2009
 
Type Article
PeerReviewed
 
Format pdf
 
Language en
 
Identifier http://ir.cftri.com/9031/1/Clinica%20Chimica%20Acta%20405%20%282009%29%2066%E2%80%9370.pdf
Basavaraj, K. H. and Darshan, M. S. and Shanmugavelu, P. and Rashmi, R. and Mhatre, A. Yuti and Dhanabal, S. P. and Rao, K. S. J. (2009) Study on the levels of trace elements in mild and severe psoriasis. Clinica Chimica Acta, 405 (1-2). pp. 66-70. ISSN 0009-8981