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Liver and erythrocyte L-aspartate: and L-alanine: 2-oxoglutarate aminotransferases of the pyridoxine deficient rat.

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Title Liver and erythrocyte L-aspartate: and L-alanine: 2-oxoglutarate aminotransferases of the pyridoxine deficient rat.
 
Creator Radhakrishnamurthy, R.
Sabry, Z. I.
 
Subject 07 Enzyme Biochemistry
 
Description The withdrawal of pyridoxine from the diet of male weading rats did not appear to affect the liver
mitochondrial L-aspartate : 2-oxoglutarate amhotransferase, but the ismnzymes in the liver supematant
and in the erythrocyte showed gradual lowering of activity. The liver kalanine : Zoxoglutarate
aminatransferase activity (mostly residing in the supernatant) showed a sharp and immediate decline,
and that of the erythrocyte exhibited a more gradual decline with the progress of deficiency.
The liver supernatant and erythrocyte aspartate aminotransferases of the deficient animals showed a
marked recowry with subcutaneous injection of pyridoxine and in vitro addition of pyridoxal-5-phosphate
to the enzyme system. The data emphasize the sensitivity of the supernatant and erythrocyte aspartate
aminotransfemses in reflecting the pyridoxine nutritional state of the rat.
 
Date 1968
 
Type Article
PeerReviewed
 
Format pdf
 
Language en
 
Identifier http://ir.cftri.com/4570/1/CANADIAN%20JOURNAL%20QF%20BIOCHEMISTRY.%20VOL.%2046%2C%2011968.pdf
Radhakrishnamurthy, R. and Sabry, Z. I. (1968) Liver and erythrocyte L-aspartate: and L-alanine: 2-oxoglutarate aminotransferases of the pyridoxine deficient rat. Canadian Journal of Biochemistry, 46. pp. 1081-1088.