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Field | Value |
Title | Recent Trends in Copper-Catalyzed C-H Amination Routes to Biologically Important Nitrogen Scaffolds |
Names |
SUBRAMANIAN, P
RUDOLF, GC KALIAPPAN, KP |
Date Issued | 2016 (iso8601) |
Abstract | Nitrogen-containing heterocycles have found remarkable applications in natural product research, material sciences, and pharmaceuticals. Although the synthesis of this interesting class of compounds attracted the interest of generations of organic chemists, simple and straightforward assembly methods based on transition-metal catalysis have regularly been elusive. The recent advancements in the development of C-H functionalization have helped in accomplishing the synthesis of a variety of complex heterocycles from simple precursors. This Focus Review summarizes the recent advances in one particular field: the copper-catalyzed C-N bond formation reactions via C-H bond functionalization to furnish a comprehensive range of nitrogen heterocycles. Applicability and synthetic feasibility of a particular reaction represent major requirements for the inclusion in this review. |
Genre | Review |
Topic | N BOND FORMATION |
Identifier | CHEMISTRY-AN ASIAN JOURNAL,11(2)168-192 |