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<p style="text-align: justify;">A new antibacterial imidazole from the marine sponge <em>Iricinia fusca</em></p>

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Title Statement <p style="text-align: justify;">A new antibacterial imidazole from the marine sponge <em>Iricinia fusca</em></p>
 
Added Entry - Uncontrolled Name Meesala, Srinu ; Indian Institute of Science Education and Research
Singh, Ruby ; Indian Institute of Science Education and Research
Watve, Milind G; Indian Institute of Science Education and Research
Naik, Dattatraya G; Abasaheb Garware College
Rajiv Gandhi Science and Technology Commission, Maharashtra, India.
 
Uncontrolled Index Term natural products chemistry
Anticancer activity; Antimicrobial; Imidazole alkaloids; Mass spectrometry; NMR; Sponge
 
Summary, etc. <p class="Abstract" style="text-align: justify;">A new imidazole alkaloid (1) along with two known compounds, variabilin (2) and iricinialactam A (3) have been isolated from the Arabian marine sponge <em>Ircinia fusca. </em>The structure of the new compound was established as 4-((1, 2-dihydroxy-5-(methyl (1-methyl-1H-imidazol-4-yl) amino) pentan-3-yl) oxy)-3, 5-dimethoxy-1-methylpyrrolidin-2-one (1) by 1D and 2D NMR, and high-resolution electrospray ionization mass spectrometry (HRESIMS). Compound 1 exhibited selective growth inhibitory activity against gram-positive bacteria <em>S. aureus</em> at 100 µg/mL.</p>
 
Publication, Distribution, Etc. Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]
2018-07-23 08:37:15
 
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http://op.niscair.res.in/index.php/IJNPR/article/view/17972
 
Data Source Entry Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]; ##issue.vol## 9, ##issue.no## 1 (2018): March, 2018
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJNPR/article/download/17972/54028
http://op.niscair.res.in/index.php/IJNPR/article/download/17972/54029
 
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