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Indian Genetic Disease Database

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Title Indian Genetic Disease Database
 
Creator Pradhan, Sanchari
Sengupta, Sengupta
Dutta, Anirban
Bhattacharyya, Kausik
Bag, Sumit K
Dutta, Chitra
Ray, Kunal
 
Subject Molecular & Human Genetics
Structural Biology & Bioinformatics
 
Description Indians, representing about one-sixth of the world population, consist of several thousands of endogamous
groups with strong potential for excess of
populations depending on its structure, reproductive recessive diseases. However, no database is available
on Indian population with comprehensive information
the genetic disorders depend on identification of the on the diseases common in the country. Toaddress this issue, we present Indian Genetic Disease Database (IGDD) release 1.0 (http://www .igdd.iicb.res.in)—an integrated and curated repository of growing number of mutation data on common genetic diseases afflicting the Indian populations. Currently the database covers 52 diseases with information on 5760 individuals carrying the mutant alleles of causal genes. Information on locus heterogeneity, type of mutation, clinical and biochemical data, geographical location and common mutations are furnished based on published literature. The database is currently designed to work best with Internet Explorer 8 (optimal resolution 1440�900) and it can be searched based on disease of interest, causal gene, type of mutation and geographical location of the patients or carriers. Provisions have beenmade for deposition of new data and logistics for regular updation of the database. The IGDD web portal, planned to be made freely available, contains user-friendly interfaces and is expected to be highly useful to the geneticists, clinicians, biologists and patient support groups of various genetic diseases.
 
Date 2011
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/54/1/NUCLEIC_ACIDS_RESEARCH%2C39%2CSupp(1)_%2CD933%2DD938%2C2011[107].pdf
Pradhan, Sanchari and Sengupta, Sengupta and Dutta, Anirban and Bhattacharyya, Kausik and Bag, Sumit K and Dutta, Chitra and Ray, Kunal (2011) Indian Genetic Disease Database. Nucleic Acids Research, 39. D933-D938.
 
Relation http://dx.doi.org/10.1093/nar/gkq1025
http://www.eprints.iicb.res.in/54/