Record Details

An Alternative to ‘propylene/Leonard linker’ for Studying Arene Interactions in Flexible Pyrazolo[3,4-d]pyrimidine Core Based Models Both at Molecular and Supramolecular Levels

EPrints@IICB

View Archive Info
 
 
Field Value
 
Title An Alternative to ‘propylene/Leonard linker’ for Studying Arene Interactions in Flexible Pyrazolo[3,4-d]pyrimidine Core Based Models Both at Molecular and Supramolecular Levels
 
Creator Avasthi, Kamlakar
Ansari, Amantullah
Kant, Ruchir
Maulik, Prakas R
Ravikumar, Krishnan
Chattopadhyay, Partha
Adhikary, Nirmal D
 
Subject Chemistry
 
Description An alternative C-3 linker to ‘propylene/Leonard linker’ is proposed for studying arene interactions in
face-to-face (offset) mode. The two new flexible symmetrical compounds with an electron deficient
pyrazolo[3,4-d]pyrimidine core and biologically important isomeric purine systems and one
dissymmetrical compound with a pyrazolo[3,4-d]pyrimidine core and electron-rich carbazole residue at
the termini of the new linker show folding due to intramolecular p–p interactions by both 1H NMR in
solution and X-ray crystallography in the solid state. Surprisingly, the replacement of the 4-
methylsulfanyl group of the dissymmetrical compound by an electron donating methoxy group shows
open conformation in the solid state by X-ray crystallography. The fifth symmetrical compound with
an electron-rich carbazole residue at the termini of new linker, however, shows the normally expected
open conformation.
 
Date 2011
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/59/1/CRYSTENGCOMM%2C13(6)%2C2039%2D2046%2C2011[104].pdf
Avasthi, Kamlakar and Ansari, Amantullah and Kant, Ruchir and Maulik, Prakas R and Ravikumar, Krishnan and Chattopadhyay, Partha and Adhikary, Nirmal D (2011) An Alternative to ‘propylene/Leonard linker’ for Studying Arene Interactions in Flexible Pyrazolo[3,4-d]pyrimidine Core Based Models Both at Molecular and Supramolecular Levels. Cryst Eng Comm, 13 (6). pp. 2039-2046.
 
Relation http://dx.doi.org/10.1039/C0CE00336K
http://www.eprints.iicb.res.in/59/