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Molecular and Biochemical Characterization of DNA Topoisomerases and Repair Enzymes from Leishmania donovani Towards Search for Plausible Therapeutic Targets

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Title Molecular and Biochemical Characterization of
DNA Topoisomerases and Repair Enzymes from
Leishmania donovani Towards Search for Plausible
Therapeutic Targets
 
Creator Banerjee, Bijoylaxmi
 
Subject Infectious Diseases and Immunology
 
Description The term “leishmaniasis”, caused by sand fly transmitted intracellular protozoan parasite Leishmania,
covers a range of disease presentations, most commonly seen in the tropical and sub tropical
countries. Leishmaniasis is not a single entity but comprises of a variety of syndromes, primarily
due to a variety of parasites affecting different populations and each related to a characteristic
vector and animal reservoirs. It is caused by species of intracellular parasite belonging to the genus
‘Leishmania’. The problem is not only complex but also cosmopolitan. Until about 60 years ago
leishmaniasis was thought to be important only in India, China, the Middle East, Southern Europe
and parts of southern America. But now it is recognized in all continents except in Australia and
Antarctica. During the past 10 years, the endemic regions have been spreading and there has been
a sharp increase in the number of recorded cases of the disease.
 
Date 2010
 
Type Thesis
NonPeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/395/1/Thesis_Bijoylaxmi_Banerjee.pdf
Banerjee, Bijoylaxmi (2010) Molecular and Biochemical Characterization of DNA Topoisomerases and Repair Enzymes from Leishmania donovani Towards Search for Plausible Therapeutic Targets. PhD thesis, Jadavpur University.
 
Relation http://www.eprints.iicb.res.in/395/