Record Details

The Effect of Anti-Prolactin Antibody on in Vitro Synthesis of a Pregnancy-Associated Rat Uterine Glycoprotein

EPrints@IICB

View Archive Info
 
 
Field Value
 
Title The Effect of Anti-Prolactin Antibody on in Vitro
Synthesis of a Pregnancy-Associated Rat Uterine
Glycoprotein
 
Creator Mehta, Monika
Chowdhury, Mridula
 
Subject Chemistry
 
Description Experiments were conducted to study the hormonal (estrogen [E2], progesterone [P4] and prolactin [PRL]), regulation of synthesis
of a pregnancy-associated glycoprotein (named Uterine Agglutinin or UA) in the Day 4 post coital (p.c.) rat uterus with antibody
administration and immunohistochemistry. Of the antibodies used, it was shown that anti-PRL antibody was the most effective
in reducing in vitro UA synthesis. The results suggested that in vitro UA synthesis could be correlated to serum PRL levels as
analyzed by radio-immunoassay. Binding studies revealed that PRL bound specifically to the stromal cells of the rat uterus
where UA is produced and localized.
 
Date 1997
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/806/1/MOLECULAR_AND_CELLULAR_BIOCHEMISTRY%2C_177(_1%2D2)%2C_131%2D138[7].pdf
Mehta, Monika and Chowdhury, Mridula (1997) The Effect of Anti-Prolactin Antibody on in Vitro Synthesis of a Pregnancy-Associated Rat Uterine Glycoprotein. Molecular and Cellular Biochemistry, 177 (1-2). pp. 131-138.
 
Relation http://dx.doi.org/10.1023/A:1006897011859
http://www.eprints.iicb.res.in/806/