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A Triterpenoid Saponin Possessing Antileishmanial Activity from the Leaves of Careya Arborea

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Title A Triterpenoid Saponin Possessing Antileishmanial Activity from the Leaves of Careya Arborea
 
Creator Mandal, Debayan
Panda, Nilendu
Kumar, Shrabanti
Banerjee, Sukdeb
Mondal, Nirup B
Sahu, Niranjan P
 
Subject Chemistry
 
Description Bioguided-fractionation of the methanol extract of the leaves of Careya arborea led to isolation of a triterpenoid saponin, designated arborenin, and characterized as 3-O-b-D-glucopyranosyl(1!2)-b-D-glucopyranosyl-2a,3b-dihydroxy-taraxast-20-en-28-oic acid (1), together with desacylescin III (2). The structures were determined on the basis of extensive 2D NMR spectroscopic analysis. The saponin
showed in vitro antileishmanial activity against Leishmania donovani (strain AG 83).
 
Date 2006
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/1083/1/PHYTOCHEMISTRY__Volume_67___Issue_2___Pages_183%2D190[145].pdf
Mandal, Debayan and Panda, Nilendu and Kumar, Shrabanti and Banerjee, Sukdeb and Mondal, Nirup B and Sahu, Niranjan P (2006) A Triterpenoid Saponin Possessing Antileishmanial Activity from the Leaves of Careya Arborea. Phytochemistry, 67 (2). pp. 183-190.
 
Relation http://dx.doi.org/10.1016/j.phytochem.2005.10.028
http://www.eprints.iicb.res.in/1083/