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Isolation of Fibronectin Type III like Peptide From Human Placental Extract Used as Wound Healer

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Title Isolation of Fibronectin Type III like Peptide From Human Placental Extract Used as Wound Healer
 
Creator Dutta Chakraborty, Piyali
Bhattacharyya, Debasish
 
Subject Structural Biology & Bioinformatics
 
Description A peptide of around 7.4 kDa has been purified from the aqueous extract of human placenta used as wound healer. Derived partial amino acid sequence from mass spectrometric analysis showed its homology with human fibronectin type III. Under nondenaturing condition, it formed aggregate, the elution pattern of which from reverse-phase HPLC was identical with that of fibronectin type III. Immuno-blot of the peptide with reference fibronectin type III-C showed strong cross reactivity. Since fibronectin type III plays important roles in wound healing, similar peptide in the extract is likely to take part in curing process.
 
Date 2005
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/1129/1/JOURNAL_OF_CHROMATOGRAPHY_B%2DANALYTICAL_TECHNOLOGIES_IN_THE_BIOMEDICAL_AND_LIFE_SCIENCES_%2C_818(_1)%2C67%2D73__[71].pdf
Dutta Chakraborty, Piyali and Bhattacharyya, Debasish (2005) Isolation of Fibronectin Type III like Peptide From Human Placental Extract Used as Wound Healer. Journal of Chromatography B, 818. pp. 67-73.
 
Relation http://dx.doi.org/10.1016/j.jchromb.2004.09.059
http://www.eprints.iicb.res.in/1129/