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Bis- and Trisuracil Nucleosides with Nucleobases Anchored to 11-, 12-, and 16-Membered Macrocyclic Scaffolds: Synthesis and Aggregation Study

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Title Bis- and Trisuracil Nucleosides with Nucleobases Anchored to 11-, 12-, and 16-Membered Macrocyclic Scaffolds: Synthesis and
Aggregation Study
 
Creator Sengupta, Jhimli
Mukhopadhyay, Ranjan
Bhattacharjya, Anup
 
Subject Chemistry
 
Description Bis- and trisuracil nucleosides, in which the nucleobases are anchored to isoxazoline ring-fused 11-, 12-,
and 16-membered macrooxacycles, were synthesized by nucleosidation of 1,2-isopropylidenefuranose
ring-fused macrocycles. The nucleosides exhibited spherical and fiber-like morphologies in water. In
one case, the morphology was significantly altered by complexation with an adenine nucleoside via
complementary base pairing.
 
Date 2007
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/1145/1/JOURNAL_OF_ORGANIC_CHEMISTRY__72_(13)_4621%2D46252007;%7B75].pdf
Sengupta, Jhimli and Mukhopadhyay, Ranjan and Bhattacharjya, Anup (2007) Bis- and Trisuracil Nucleosides with Nucleobases Anchored to 11-, 12-, and 16-Membered Macrocyclic Scaffolds: Synthesis and Aggregation Study. The Journal of Organic Chemistry, 72 (13). pp. 4621-4625.
 
Relation http://dx.doi.org/10.1021/jo062554b
http://www.eprints.iicb.res.in/1145/