Record Details

Genetic Toxicology of a Paradoxical Human Carcinogen, Arsenic: a review

EPrints@IICB

View Archive Info
 
 
Field Value
 
Title Genetic Toxicology of a Paradoxical Human Carcinogen, Arsenic: a review
 
Creator Basu, A
Mahata, Julie
Gupta, S
Giri, Ashok K
 
Subject Molecular & Human Genetics
 
Description Arsenic is widely distributed in nature in air, water and soil in the form of either metalloids or chemical compounds. It is
used commercially, as pesticide, wood preservative, in the manufacture of glass, paper and semiconductors. Epidemiological
and clinical studies indicate that arsenic is a paradoxical human carcinogen that does not easily induce cancer in animal
models. It is one of the toxic compounds known in the environment. Intermittent incidents of arsenic contamination in ground
water have been reported from several parts of the world. Arsenic containing drinking water has been associated with a variety
of skin and internal organ cancers. The wide human exposure to this compound through drinking water throughout the world
causes great concern for human health. In the present review, we have attempted to evaluate and update the mutagenic and
genotoxic effects of arsenic and its compounds based on available literature. © 2001 Elsevier Science B.V. All rights reserved.
 
Date 2001
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/1148/1/MUTATION_RESEARCH%2DREVIEWS_IN_MUTATION_RESEARCH__Volume_488___Issue_2___Pages_171%2D194[39].pdf
Basu, A and Mahata, Julie and Gupta, S and Giri, Ashok K (2001) Genetic Toxicology of a Paradoxical Human Carcinogen, Arsenic: a review. Mutation Research, 488 (2). pp. 171-194.
 
Relation http://dx.doi.org/10.1016/S1383-5742(01)00056-4
http://www.eprints.iicb.res.in/1148/